Researcher Profile

Field: Molecular Diagnostics

Main Research: Diagnostics biosensors

Experience: My research is devoted to exploring new ways and principles for the detection and analysis of biomolecules with the goal to achieve better performance than currently possible by state-of-the-art methods (e.g. in terms of sensitivity or ease of use). One focus is on exploiting magnetic principles, including both heterogeneous assays comprising magnetoresistive transducers as well as magnetic nanoparticles for homogeneous assays. Furthermore, I’m investigating the quantification of biomolecules within the dermal interstitial fluid by electrochemical methods. In that regard, I’m currently coordinating the European project ELSAH, which targets to develop a microneedle-based smart patch for the continuous monitoring of health and well-being related molecular biomarkers by an integrated smart-patch solution.

• 2005-now: Scientist
  AIT Austrian Institute of Technology GmbH / Austria

• Ultrahigh-Density Nanowire Arrays Grown in Self-Assembled Diblock Copolymer Templates
  Author(s): Thurn-Albrecht, T.; Schotter, J.; Kastle, G.A.; Emley, N.; Shibauchi, T.; Krusin-Elbaum, L.; Guarini, K.; Black, C.T.; Tuominen, M.T.; Russell, T.P.
  Journal: Science, 290 (2000) ; 2126-2129
• Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection
  Author(s): Schotter, J.; Kamp, P.B.; Becker, A.; Pühler, A.; Reiss, G.; Brückl, H.
  Journal: Biosensors & Bioelectronics, 19 (2004) ; 1149-1156
• Modeling and development of a biosensor based on optical relaxation measurements of hybrid nanoparticles
  Author(s): Schrittwieser, S.; Ludwig, F.; Dieckhoff, J.; Soulantica, K.; Viau, G.; Lacroix, L.-M.; Lentijo, S.Mozo; Boubekri, R.; Maynadié, J.; Huetten, A.; Brueckl, H.; Schotter, J.
  Journal: ACS Nano, 6 (2012) ; 791-801
• Magnetoresistive-based real-time cell phagocytosis monitoring
  Author(s): Shoshi, A.; Schotter, J.; Schroeder, P.; Milnera, M.; Ertl, P.; Charwat, V.; Purtscher, M.; Heer, R.; Eggeling, M.; Reiss, G.; Brueckl, H.
  Journal: Biosensors & Bioelectronics, 36 (2012) ; 116-122
• Direct protein detection in the sample solution by monitoring rotational dynamics of nickel nanorods
  Author(s): Schrittwieser, S.; Ludwig, F.; Dieckhoff, J.; Tschoepe, A.; Guenther, A.; Richter, M.; Huetten, A.; Brueckl, H.; Schotter, J.
  Journal: Small, 10 (2014) ; 407-411
• Homogeneous Biosensing Based on Magnetic Particle Labels
  Author(s): Schrittwieser, S.; Pelaz, B.; Parak, W. J.; Lentijo-Mozo, S.; Soulantica, K.; Dieckhoff, J.; Ludwig, F.; Guenther, A.; Tschope, A.; Schotter, J.;
  Journal: Sensors , 16 (2016) ; 828
• Direct protein quantification in complex sample solutions by surface-engineered nanorod probes
  Author(s): Schrittwieser, S; Pelaz, B; Parak, W. J.; Lentijo-Mozo, S.; Soulantica, K.; Dieckhoff, J.; Ludwig, F.; Schotter, J.
  Journal: Scientific Reports, 7 (2017) ; 4752
• Applications, Surface Modification and Functionalization of Nickel Nanorods
  Author(s): Schrittwieser, S; Reichinger, D.; Schotter, J.
  Journal: Materials, 11 (2018) ; 45
• Applications, Surface Modification and Functionalization of Nickel Nanorods
  Author(s): Schrittwieser, S; Reichinger, D.; Schotter, J.
  Journal: Materials, 11 (2018) ; 45

• Optical measurement method for molecular detection using relaxation measurement in optically anisotropic nanoparticles and device for performing the method (AT503845, EP2147314, CN101743475, US9068978, dates from EP patent)
  Inventor: Schotter, J.; Bethge, O.; Maier, T.; Brueckl, H.
  Submission Date: 27.03.2008
  Issue Date: 15.04.2015
• Apparatus for enhancing the reaction efficiency, especially the binding efficiency, between molecules and molecular moieties (AT503573, EP2004317)
  Inventor: Heer, R.; Eggeling, M.; Schotter, J.; Noehammer, C.; Pichler, R.; Mansfeld, M.
  Submission Date: 13.04.2006
  Issue Date: 15.11.2007
• Nanocylinder arrays (US7190049)
  Inventor: Touminen, M.; Schotter, J.; Thurn-Albrecht, T.; Russell, T.P.
  Submission Date: 23.03.2001
  Issue Date: 13.03.2007

• Publications AIT publications database