Researcher Profile

Field: Molecular Diagnostics

Main Research: Diagnostics biosensors

Experience: My research is devoted to exploiting magnetic principles for the detection and analysis of biomolecules. This includes both heterogeneous assays comprising magnetoresistive transducers as well as magnetic nanoparticles for homogeneous assays. The latter concept is based on optically observing changes in the magnetorelaxation of rod-shaped nanoparticle probes on specific binding of target molecules, which we successfully demonstrated within the frame of the FP7 NMP project NAMDIATREAM. This project was recently awarded as the best of more than 1000 European projects in the field of nanotechnologies and advanced materials (FutureFlash! Best Project competition 2015).

• 2005-now: Scientist
  AIT Austrian Institute of Technology GmbH / Austria

• Ultrahigh-Density Nanowire Arrays Grown in Self-Assembled Diblock Copolymer Templates
  Author(s): Thurn-Albrecht, T.; Schotter, J.; Kastle, G.A.; Emley, N.; Shibauchi, T.; Krusin-Elbaum, L.; Guarini, K.; Black, C.T.; Tuominen, M.T.; Russell, T.P.
  Journal: Science, 290 (2000) ; 2126-2129
• Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection
  Author(s): Schotter, J.; Kamp, P.B.; Becker, A.; Pühler, A.; Reiss, G.; Brückl, H.
  Journal: Biosensors & Bioelectronics, 19 (2004) ; 1149-1156
• Modeling and development of a biosensor based on optical relaxation measurements of hybrid nanoparticles
  Author(s): Schrittwieser, S.; Ludwig, F.; Dieckhoff, J.; Soulantica, K.; Viau, G.; Lacroix, L.-M.; Lentijo, S.Mozo; Boubekri, R.; Maynadié, J.; Huetten, A.; Brueckl, H.; Schotter, J.
  Journal: ACS Nano, 6 (2012) ; 791-801
• Magnetoresistive-based real-time cell phagocytosis monitoring
  Author(s): Shoshi, A.; Schotter, J.; Schroeder, P.; Milnera, M.; Ertl, P.; Charwat, V.; Purtscher, M.; Heer, R.; Eggeling, M.; Reiss, G.; Brueckl, H.
  Journal: Biosensors & Bioelectronics, 36 (2012) ; 116-122
• Direct protein detection in the sample solution by monitoring rotational dynamics of nickel nanorods
  Author(s): Schrittwieser, S.; Ludwig, F.; Dieckhoff, J.; Tschoepe, A.; Guenther, A.; Richter, M.; Huetten, A.; Brueckl, H.; Schotter, J.
  Journal: Small, 10 (2014) ; 407-411
• Homogeneous Biosensing Based on Magnetic Particle Labels
  Author(s): Schrittwieser, S.; Pelaz, B.; Parak, W. J.; Lentijo-Mozo, S.; Soulantica, K.; Dieckhoff, J.; Ludwig, F.; Guenther, A.; Tschope, A.; Schotter, J.;
  Journal: Sensors , 16 (2016) ; 828
• Direct protein quantification in complex sample solutions by surface-engineered nanorod probes
  Author(s): Schrittwieser, S; Pelaz, B; Parak, W. J.; Lentijo-Mozo, S.; Soulantica, K.; Dieckhoff, J.; Ludwig, F.; Schotter, J.
  Journal: Scientific Reports, 7 (2017) ; 4752

• Optical measurement method for molecular detection using relaxation measurement in optically anisotropic nanoparticles and device for performing the method (AT503845, EP2147314, CN101743475, US9068978, dates from EP patent)
  Inventor: Schotter, J.; Bethge, O.; Maier, T.; Brueckl, H.
  Submission Date: 27.03.2008
  Issue Date: 15.04.2015
• Apparatus for enhancing the reaction efficiency, especially the binding efficiency, between molecules and molecular moieties (AT503573, EP2004317)
  Inventor: Heer, R.; Eggeling, M.; Schotter, J.; Noehammer, C.; Pichler, R.; Mansfeld, M.
  Submission Date: 13.04.2006
  Issue Date: 15.11.2007
• Nanocylinder arrays (US7190049)
  Inventor: Touminen, M.; Schotter, J.; Thurn-Albrecht, T.; Russell, T.P.
  Submission Date: 23.03.2001
  Issue Date: 13.03.2007

• Publications AIT publications database
• CV as pdf