Researcher Profile

Mag. Dr. Ivan Barisic

Mag. Dr. Barisic

Function

Scientist

Center

Health & Bioresources

Business Unit

Molecular Diagnostics

E-Mail

Ivan.Barisic(at)ait.ac.at

Phone

+43 664 88390643

Address

Muthgasse 11, 1190 Vienna

Career

Area: Biomedical & Biomolecular Health Solutions

Field: Molecular Diagnostics

Main Research: Development of DNA-based Multiplex Detection

Experience: Dr. Barisic has profound experience in the fields of biotechnology and clinical microbiology. He has developed several novel DNA detection principles and diagnostic assays. To enable a smooth translation of this basic research into future applications and identify customer needs, close collaborations with medical centres were established. As a consequence, Dr. Barisic has also become an expert concerning human pathogens, antibiotic resistance and virulence factors. He initiated the H2020 project FAPIC (www.fapic.eu) based on his novel detection technologies. The goal of FAPIC is to develop a single diagnostic test for all clinically important pathogens (bacteria, viruses and fungi), antibiotic resistance genes and virulence factors. The diagnostic system will be evaluated in a clinical intervention study in university hospitals in Zagreb and Hasselt. In addition, Dr. Barisic initiated and coordinates the H2020 FETopen project MARA (www.maraproject.eu). The goal of this highly ambitious project is to develop three radically novel breakthrough technologies. The first technology concerns a novel sensor class aiming the design of autonomous detection oligonucleotides. Second, a directed design concept for artificial enzymes using DNA nanostructures such as DNA origami is being evaluated. Finally, these technologies should be combined to generate a DNA robot that can specifically identify cells and destroy them.

  • 2005-2007: Diploma student
    Department of Microbial Ecology DOME / Austria
  • 2007-2008: Technical assistent
    Casa the los Tres Mundos / Nicaragua
  • 2009-2013: PhD student
    AIT / Austria
  • 2011-2011: Visiting scientist
    Uppsala University / Sweden
  • 2013-now: Scientist
    AIT / Austria

Publications

  • Multiplex detection of antibiotic resistance genes using padlock probes
    Author(s): Ivan Barišic, Silvia Schoenthaler, Rongqin Ke, Mats Nilsson, Christa Noehammer, Herbert Wiesinger-Mayr
    Journal: Diagnostic Microbiology and Infectious Disease (2013)
  • High diversity of beta-lactamases in the General Hospital Vienna verified by whole genome sequencing and statistical analysis
    Author(s): Ivan Barišic, Dieter Mitteregger, Alexander M. Hirschl, Christa Noehammer, Herbert Wiesinger-Mayr
    Journal: Infection, Genetics and Evolution (2014)
  • An Impedimetric Sensor for Real-Time Detection of Antibiotic Resistance Genes Employing Rolling Circle Amplification
    Author(s): T. Maier, K. Kainz, I. Barisic, R. Hainberger
    Journal: International Journal of Electrochemical Science (2015)
  • Fast and highly specific DNA-based multiplex detection on a solid support
    Author(s): Barišic I, Kamleithner V, Schönthaler S, Wiesinger-Mayr H
    Journal: Appl Microbiol Biotechnol (2015)
  • Multiplex characterization of human pathogens including species and antibiotic-resistance gene identification
    Author(s): Barišic I, Petzka J, Schoenthaler S, Vierlinger K, Noehammer C, Wiesinger-Mayr H.
    Journal: J Med Microbiol (2016)
  • FAST AND HIGHLY SPECIFIC DNA-BASED MULTIPLEX DETECTION
    Inventor: Ivan Barisic
    Submission Date: 23.09.2014
    Issue Date: 23.09.2014
  • Autonomous sensing molecules
    Inventor: Ivan Barisic
    Submission Date: 27.11.2015
    Issue Date: 27.11.2015
  • Nanostructures with catalytic activity
    Inventor: Ivan Barisic
    Submission Date: 27.11.2015
    Issue Date: 27.11.2015
  • Molecular robot
    Inventor: Ivan Barisic
    Submission Date: 27.11.2015
    Issue Date: 27.11.2015

Further Information

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