Mobile molecular diagnostics requires miniaturised and automated devices with high analytical performance, enabling earlier and more accurate disease detection based on molecular blood and saliva tests. AIT has extensive expertise in the integration of biomarkers, sensors, microfluidics, molecular detection reactions as well as readout electronics and process management. System integration is aimed at optimising the interaction between the individual components, while also ensuring simple and user-friendly operation.

Our services

  • Integration of external technologies with AIT's molecular diagnostic technologies (e.g. biosensors with biochemical tests, sample preparation with analysis systems) 
  • Development of point-of-care systems and demonstratorsValidation of diagnostic systems (in cooperation with clinical partners in human and veterinary medicine)
  • Prototyping of microfluidic structures in polymer substrates (micromilling)

Publications

Zirath H, Brandhoff L, Coll A, Schnetz G, Spittler A, Wiesinger-Mayr H, Vellekoop MJ, Redl H, Peham JR. A microfluidic system with chipintegrated micro-syringes and ultrasonic handling of magnetic beads. MicroTAS. 2014, in press.

Zirath H, Peham J, Schnetz G, Brandhoff L, Spittler A, Wiesinger-Mayr H, Vellekoop MJ, Redl H. A disposable microfluidic chip for rapid and sensitive detection of plasma biomarkers. Proc Eng. 2014(87): 496-499. doi: 10.1016/j.proeng.2014.11.410

Peham JR, Recnik L, Grienauer W, Vellekoop MJ, Noehammer C, Wiesinger-Mayr H. Disposable microfluidic chip for rapid pathogen identification with DNA microarrays. Microsyst Technol. 2012(18): 311-318. doi:10.1007/s00542-011-1401-0

Peham JR, Vellekoop MJ, Noehammer C, Wiesinger-Mayr H. PCR Product Detector with LED-Photodiode Fluorescence Sensing in a Nanoliter Flow-Cell for the High-Throughput Detection of Double-Stranded DNA. Proc Engineering. 2011(25): 936-939. doi:10.1016/j.proeng.2011.12.230

Peham JR, Grienauer W, Steiner H, Heer R, Vellekoop MJ, Noehammer C, Wiesinger-Mayr H. Long target droplet polymerase chain reaction with a microfluidic device for high-throughput detection of pathogenic bacteria at clinical sensitivity. Biomed Microdevices. 2011(13): 463-473. doi: 10.1007/s10544-011-9514-x